It is important to diagnose other diseases, some of which are life threatening that can mimic GERD. A cardiac workup and gallbladder ultrasound for instance could be considered.
An upper GI x-ray looks at the anatomy and function of the esophagus and stomach, and can be helpful.
An upper endoscopy of the esophagus and stomach is a critical part of the evaluation of patients with GERD. Its main aim is to detect complications of GERD, the presence of which often influences therapeutic decisions.